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Peony might slow blood clotting. Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R., and Zwickey, H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. View abstract. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. All rights reserved. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. A., Braun, T. M., and Jacobson, J. J. Lancet 1990;335(8697):1060-3. J Neuroophthalmol. Benge E, Shah P, Yamaguchi L, Josef V. Trick or Treat? View abstract. Black licorice can have serious side effects when eaten in large amounts. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. Luper, S. A review of plants used in the treatment of liver disease: part two. View abstract. Cochrane Database Syst Rev 2004;4:CD002291. Concomitant Use of High-dose Methotrexate and Glycyrrhizin Affects Pharmacokinetics of Methotrexate, Resulting in Hepatic Toxicity. View abstract. Z. 2005;25(6):540-542. View abstract. Some medications are changed and broken down by the liver. View abstract. View abstract. Ann Noninvasive Electrocardiol. Licorice, tobacco chewing, and hypertension. Hyodo T, Taira T, Kumakura M, et al. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. J Pharmacobiodyn 1983;6:153-60. . N Engl J Med 1999;341:1158. J Assoc Physicians India 1989;37(10):647. View abstract. 2017;109:182-190. Pharm Biol 2021;59(1):1276-1285. Luo, Y. G., Liu, Y. Q., and Hu, J. View abstract. If you take birth control pills along with peony, use an additional form of birth control such as a condom. Postgrad Med 2017;129(3):329-31. Licorice can decrease how quickly the body breaks down corticosteroids. Chamberlain, J. J. and Abolnik, I. Clin Ter 1990;132(1):55-58. View abstract. Results of a double-blind placebo controlled comparative study]. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Das SK, Das V, Gulati AK, and et al. Int Urol Nephrol. Neth J Med 2005;63:119-20. J Clin Ther Med 1999;15:499-523. Antiviral Res 12-11-1988;10(6):289-298. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). Side effects, toxicity, and interactions. Medicinal herbs: modulation of estrogen action. View abstract. Zhong Yao Cai 2000;23:557-60. . 1. 2004;24(12):1084-1086. View abstract. Gut 1973;14(9):711-715. Report of 2 cases and review of the literature. Eur J Pharm Sci. Leem, K., Kim, H., Boo, Y., Lee, H. S., Kim, J. S., Yoo, Y. C., Ahn, H. J., Park, H. J., Seo, J. C., Kim, H. K., Jin, S. Y., Park, H. K., Chung, J. H., and Cho, J. J. The yellow-brown thick-branched roots are used as medicine. Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S. To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. J Telemed Telecare. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. Researchers from the University of Minnesota studied 50 atopic dogs in a randomized, double-blind, placebo-controlled trial. Armanini, D., Mattarello, M. J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., and Palermo, M. Licorice reduces serum testosterone in healthy women. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. This information may not fit your specific health circumstances. Black licorice contains a compound that comes from licorice root that can lower your potassium levels. Phytother Res 2006;20(8):687-695. View abstract. N Engl J Med 1968;278(25):1381-1383. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. View abstract. View abstract. View abstract. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . O'Connell, R. L., White, I. R., White, J. M., and McFadden, J. P. Liquorice extract in a cosmetic product causing contact allergy. Holtmann G, Madisch A, Juergen H, et al. J Clin Psychopharmacol 1997;17(3):234-235. J Biol Response Mod 1985;4:551-84. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. B. View abstract. "Water pills" can also decrease potassium levels. Eur.Arch.Paediatr.Dent 2010;11(6):274-278. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Neurology 2010;75(21):1939-1941. Hussain RM. View abstract. Hawrelak, J. Mol.Nutr Food Res 2011;55(2):318-327. Liang, R. N., Liu, J., and Lu, J. View abstract. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. But, she survived . Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. An Med Interna 1995;12(1):33-35. Here are a few of them: . View abstract. Nephron 2002;90:240. . Am J Respir.Cell Mol.Biol. Effects of total glucosides of peony on immunological hepatic fibrosis in rats. View abstract. Am J Epidemiol 2001;153:1085-8. Lee, S. M., Li, M. L., Tse, Y. C., Leung, S. C., Lee, M. M., Tsui, S. K., Fung, K. P., Lee, C. Y., and Waye, M. M. Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway. is tatcha violet c brightening serum safe for pregnancy is tatcha violet c brightening serum safe for pregnancy Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. J Clin Hypertens (Greenwich) 2008;10:153-7. It's not suggested to take St. John's wort if you take blood thinners. Man SC, Li XB, Wang HH, et al. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. Indian J Med Res 1993;98:69-74. View abstract. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. Altern Med Rev 1999;4(3):178-188. View abstract. Biol Pharm Bull 2000;23:199-203.. View abstract. View abstract. View abstract. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Mamgain RK, Gupta M, Mamgain P, et al. Licorice roots can be consumed directly to get relief from cough and sore throat. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. Exp Clin Endocrinol Diabetes 2003;111:341-3. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Contemp Dent Pract 2010;11(1):E088-E094. Sheth, V. M. and Pandya, A. G. Melasma: a comprehensive update: part II. Schleimer, R. P. Potential regulation of inflammation in the lung by local metabolism of hydrocortisone. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. 2011;25(2):312-313. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. View abstract. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. Yorgun, H., Aksoy, H., Sendur, M. A., Ates, A. H., Kaya, E. B., Aytemir, K., and Oto, A. Brugada syndrome with aborted sudden cardiac death related to liquorice-induced hypokalemia. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. Zhonghua Yi Xue Za Zhi 1983;63:477-81. View abstract. Practitioner 1973;210:820-3. Zhang W, Dai SM. Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Warfarin is used to slow blood clotting. Abe Y, Ueda T, Kato T, Kohli Y. . Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Man SC, Li XB, Wang HH, et al. View abstract. Licorice might decrease how well cisplatin works. Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest. Isr J Dent Sci 1989;2(3):153-157. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. Deglycyrrhizinated liquorice in aphthous ulcers. For women taking oral contraceptives, there is a very small chance that this can counteract the effects of this medication. Not too many side effects of peony tea that we need to worry about. Int Immunopharmacol. Select a condition to view a list of vitamins. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. B., and Zhang, Z. J. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. Licorice might change how these pumps work and change how much medication stays in the body. Madisch A, Holtmann G, Mayr G, et al. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. NOW Supplements, Licorice Root (Glycyrrhiza glabra) 450 mg, Herbal Supplement, 100 Veg Capsules 208. Lee, S. J., Lee, I. S., and Mar, W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. Clin Ther 1999;21(12):2080-2090. Abe K, Higurashi T, Takahashi M, et al. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. View abstract. View abstract. View abstract. View abstract. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Am Coll.Nutr 2007;26(3):209-218. Biol Pharm Bull. 1991;78(1-2):1-6. Eisenburg, J. Berlango Jimenez A., Jimenez Murillo L., Montero Perez F. J., Munoz Avila J. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. Strandberg TE, Andersson S, Jarvenpaa AL, et al. Some birth control pills contain estrogen. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. Mayo Clin Proc 2003;78:767-8. View abstract. Eagon PK, Elm MS, Hunter DS, et al. 2013 Sep;117(3):614-21. View abstract. Sato H, Goto W, Yamamura J, et al. The chemicals in licorice are thought to . View abstract. 2019;35:329-41. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. Amaryan G, Astvatsatryan V, Gabrielyan E, et al. 1991;11(4):199-202, 195. View abstract. Contact Dermatitis 2008;59(1):52. View abstract. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. Fitoterapia 2004;75:45-9.. View abstract. Am J Chin Med 2005;33(5):747-758. Exp Neurol 1997;146:518-25. View abstract. Cancer Res 2000;60:5704-9.. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Int Hepatol Comm 1997;233-238. A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. View abstract. Gut 1969;10:299-302. 1993;13(10):591-3, 579. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. Licorice-Induced Hypokalemia: A Case Report. Phytother Res 2008;22:563-5. Some possible side effects with oral use include rash, itching, nasal symptoms, or stomach discomfort, but these are uncommon. Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. Medicine (Baltimore) 2018;97(11):e0073. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. View abstract. View abstract. Hattori, M., Sakamoto, T., Kobashi, K., and Namba, T. Metabolism of glycyrrhizin by human intestinal flora. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. Pharmacol Biochem Behav 1993;45:719-23. . View abstract. No side effects or changes in liver function tests occurred during the study. We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . Some medications are changed and broken down by the liver. Antiviral Res 1987;7(3):127-137. and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Mouthwash Containing Glycyrrhiza uralensis Extract for Preventing Dental Caries. View abstract. Murck H, Lehr L, Hahn J, Braunisch MC, Jezova D, Zavorotnyy M. Adjunct Therapy With Glycyrrhiza Glabra Rapidly Improves Outcome in Depression-A Pilot Study to Support 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Inhibition as a New Target. He X, Xing D, Ding Y, et al. View abstract. View abstract. Planta Med 2003;69(12):1113-1118. View abstract. Lancet 2003;361:2045-6.. View abstract. View abstract. ['Licorice hypertension' also caused by licorice tea]. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. It is used for stomach pain, abdominal pain and acute pain of gastrocnemius muscle contracture, etc. Phytother Res. Asian Medical Journal 1984;26(7):423-438. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Goultschin, J., Palmon, S., Shapira, L., Brayer, L., and Gedalia, I. Clin Pharmacol Ther 1996;59:62-71. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Kwon S, Jin C, Cho SY, et al. We currently have no information for PEONY overview. Immunopharmacology 1999;41(3):169-181. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. View abstract. J Ethnopharmacol 2004;94:339-44. . Armanini D, Bonanni G, Mattarello MJ, et al. 2020;2020:8401239. . Biol Pharm Bull. View abstract. Mol Cell Endocrinol. Deglycyrrhizinated liquorice in duodenal ulcer. Licorice might change how quickly the liver breaks down these medications. Licorice is an herb that grows in parts of Europe and Asia. Asia Pac.J Clin Nutr 2008;17(1):17-22. Lee, I. T., Lee, W. J., Tsai, C. M., Su, I. J., Yen, H. T., and Sheu, W. H. Combined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndrome. View abstract. View abstract. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. Pharm Biol. View abstract. Farese RV Jr, Biglieri EG, Shackleton CH, et al. Hajiaghamohammadi, A. Read more. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. October 15, 2021. Yoon JY, Cha JM, Hong SS, et al. Chin J Integr Med 2022. View abstract. Kitagawa, I., Chen, W. Z., Hori, K., Harada, E., Yasuda, N., Yoshikawa, M., and Ren, J. View abstract. J Clin Psychopharmacol 2008;28(3):264-370. Licorice consumption and serum testosterone in healthy man. 2003;23(8):593-595. Int J Dermatol 1999;38:387-92 . View abstract. Mol Nutr Food Res 2006;50(11):1080-1086. 2000;20(1):38-41. Kinoshita T, Maruyama K, Yamamoto N, Saito I. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. View abstract. The U.S. Food and Drug . View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Blood Press 2009;18:192-5. Therapeutic Research Faculty 2020. Liquorice supplements Low doses of liquorice can induce hypertension encephalopathy. View abstract. Yu C, Fan X, Li Z, Liu X, Wang G. Efficacy and safety of total glucosides of paeony combined with acitretin in the treatment of moderate-to-severe plaque psoriasis: a double-blind, randomised, placebo-controlled trial. $9.44 $ 9. Am J Nephrol 2000;20:145-8. J Intern Med 1999;245:307-10. Licorice might increase how quickly midazolam is broken down by the body. Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. A 2020 review found that licorice root extract can help reduce the growth of . Liapina LA, Ammosova IaM, Novikov VS, et al. Pathogenetic considerations and presentation of a clinical case]. 2014 Jan;35(1):87-99. Also for White Peony, the plant that is used in traditional . View abstract. Clin Exp Obstet Gynecol 2013;40(1):141-143. View abstract. Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells. Kroes, B. H., Beukelman, C. J., van den Berg, A. J., Wolbink, G. J., van Dijk, H., and Labadie, R. P. Inhibition of human complement by beta-glycyrrhetinic acid. View abstract. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. View abstract. View abstract. View abstract. View abstract. J Altern Complement Med 2010;16(10):1065-1071. Bell ZW, Canale RE, Bloomer RJ. 2008;9(3):88-98. de Klerk GJ, Nieuwenhuis G, Beutler JJ. View abstract. 83rd Annual Meeting of the Endocrine Society, June 20-23 2001;abstract P1-573. Some believe it may also increase estrogen and prolactin levels in women, though more research is warranted. Case Rep Emerg Med. Life Sci 1993;53(5):PL63-8. Lancet 2000;355(9198):134-138. 4-14-2001;145(15):744-747. Cureus 2021;13(7):e16454. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. J Contemp.Dent Pract. [Application of dannang recipe no. Bruynzeel DP. J Nat Prod 1980;43(2):259-269. According to research, the combination of . Serra, A., Uehlinger, D. E., Ferrari, P., Dick, B., Frey, B. M., Frey, F. J., and Vogt, B. Glycyrrhetinic Acid decreases plasma potassium concentrations in patients with anuria. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin; Clopidogrel; Warfarin; St. John's wort. J Cardiovasc.Surg (Torino) 2000;41(4):631-632. View abstract. View abstract. J Clin Psychopharmacol 2008;28(3):264-370. Patel P, Aknouk M, Dawson A, et al. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. QJM 2011;104(12):1093-1095. Hum Exp Toxicol 2012;31(12):1295-1298. When eaten in large quantities, black licorice can cause serious health issues. Biol Pharm Bull 2007;30(11):2191-2195. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. mentioned adverse effects and recurrence rates. West J Med 1997;167(3):184-185. van der Zwan A. Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials. Crit Care 2011;15(1):R64. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. BJU Int 2000;85:481-5. 2014 Jun;20(6):516-20. View abstract. View abstract. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. Hypertension encephalopathy after liquorice ingestion. 2010;16(4):216-218. Be sure to have your blood checked regularly. Removes excess melanin: Licorice extract brightens the skin in another way, too. Prospective study]. Int J Nurs Stud 2016;63:9-17. Nat Prod Res 2007;21(14):1234-1241. View abstract. N Engl J Med 1990;322:850. View abstract. J Steroid Biochem Mol Biol 1994;49:81-5. Meng Xiangrui is an academic researcher. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. View abstract. Peony might have some of the same effects as estrogen. Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. Licorice might decrease the effects of warfarin. Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Part 2: Effect of glycyrrhizic acid on the course of illness]. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. Dai DW, Singh I, Hershman JM. Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. View abstract. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. Ed. Drugs & Vitamins . Phytother Res. Paeonia lactiflora : Peony is another popular anti-androgenic herb. Nephron 2002;90:240. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. Licorice can decrease potassium levels. Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. View abstract. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. View abstract. View abstract. Effect of shakuyaku-kanzoh-toh, a prescription composed of shakuyaku (Paeoniae Radix) and kanzoh (Glycyrrhizae Radix) on guinea pig ileum. Medicinal uses of licorice through the millennia: the good and plenty of it. View abstract. View abstract. Steroids 2005;70(8):538-542. View abstract. This can be severe. View abstract. View abstract. An Bras Dermatol 2010;85(5):613-620. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Mumoli, N. and Cei, M. Licorice-induced hypokalemia. Kumada T, et al. What are the side-effects of taking liquorice? J Pharmacobiodyn 1984;7:304-11. Note: Results may vary from person to person, depending on the skin type. View abstract. View abstract. Kim, H. J., Chang, E. J., Bae, S. J., Shim, S. M., Park, H. D., Rhee, C. H., Park, J. H., and Choi, S. W. Cytotoxic and antimutagenic stilbenes from seeds of Paeonia lactiflora. Information from this source is evidence-based and objective, and without commercial influence. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) .